• 无工作经验
  • 硕士
  • 招1人
  • 11-09 发布

职位描述

职位描述: We are seeking an experienced and highly motivated scientist with strong hands-on experience in antibody and protein engineering to join us. A main objective for this candidate will be to independently conduct therapeutic antibody humanization and optimization projects using structure guided focused design, phage display and various biophysical characterization techniques. The candidate should be current with the latest technology developments and be able to propose and implement process improvement technologies to aid reduction in cycle time and improve attrition rates. The candidate will serve as project team leader to coordinate research activities in a multi-disciplinary setting. This will involve data presentation in well-organized written and oral formats at various team, group, and project review meetings. Responsibilities:Lead engineering and humanization of novel antibody therapeutics, use of techniques employing molecular biology, biochemistry, structural modeling for antibody affinity maturation and antibody stabilization.Drive efforts to design and optimize bispecifc antibody formats to support cell therapy and therapeutic antibody programs.Serve as project team leader, manage project progress and timeline, and provide regular updates in achieving the specific objectives of the respective research projects.Work cross-functionally as part of internal multi-disciplinary teams, coordinating lead isolation, optimization and characterization.Qualifications:PhD with 2-3 years, or MS with 5-7 years of experience in Molecular Biology, Biochemistry, Structural Biology or related discipline.Industry experience strongly preferred, prior experience of therapeutic antibody discovery projects a plus.Expertise utilizing techniques for antibody engineering, antibody humanization, affinity maturation and antibody stabilization. Familiarity with antibody properties and sequences, hands-on experience using MOE, Discovery Studio, Schrodinger, Rosetta or similar tools for protein structure modeling a strong plus.Excellent data management, written and presentation skills and a team player. 职能类别: 生物工程/生物制药

联系方式

南京市江宁区大学城工业园雍熙路28号

公司信息

金斯瑞介绍 GenScript USA Inc. 2002年成立于美国新泽西州医药产业带, 作为集研发、生产、销售于一体的全球领先的生物技术公司和生物药研发CRO公司,GenScript为客户提供基因、多肽、蛋白、抗体、细胞系等药物研发所需的生物试剂,和新药筛选、小分子药物和大分子药物开发等早期药物研发服务。公司与各种类型的制药公司、生物技术公司和学术研究机构协作,提高他们的研究效率和核心竞争力,从而提升他们针对各种疾病的研究能力,缩短药物研发周期,最终改善人类健康和生活。公司已发展成为具有世界***水平的生物CRO公司和全球领先的基因合成供应商,且目前分别在法国、日本和中国设有分部。目前,金斯瑞在南京江宁高新技术开发区的注册资金高达1亿美元。 金斯瑞的人员结构 公司现有员工1200余人,其中本科硕士及以上学历者占公司员工总数70%以上。每个部门都有来自欧美著名院校毕业的专家,每位专家都有在欧美著名医药企业或生物技术服务公司多年的服务、管理经验,并在各自的领域内取得丰硕的成果。 金斯瑞的特色 中国最大的生物 医药研发外包服务企业(CRO) 全球领先的基因合成服务供应商 行业内最先进的抗体服务承诺 为小分子及大分子早期药物研发,提供一站式的生物外包服务 主要生产和研发部门位于在中国,拥有先进的设备和面积超过108,000 平方英尺的实验室 24小时在线客服 ISO 9001:2000 认证,AAALAC 认证,严格的客户知识产权保护体系 拥有先进的生物信息学工具和强大的IT技术支持,为客户提供增值服务 客户遍及全球70多个国家的科研机构、***制药公司和生物技术公司 丰富经验的科研团队及管理团队

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