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5-7年经验 -
博士 -
招若干人 -
11-09 发布
职位描述
职位描述： Biosynergics Incorporation (BSI) is a Nanjing-based start-up biotech company focusing on the discovery and development of the innovative biologics for the unmet medical needs. With our proprietary H3 (High-throughput High-content High-efficiency) antibody platform and SynAbTM technology, BSI is committed to the development of biological molecules with superior drug properties and/or with novel mechanism of actions to known and novel drug targets.Location: Greater Philadelphia, USA and/or Nanjing, ChinaJob Responsibilities1. Responsible for establishing mammalian cell line development platform and generating high producing cell lines for the production of recombinant proteins, including fusion protein and monoclonal antibody.2. Performing key activities associated with production cell line development including transfection, selection, single cell cloning, high throughput screening, characterization of clonal cell lines using scale-down models, cell banking, and cell line stability studies.3. Developing and optimizing new protein expression platform including designing, constructing, and evaluating novel expression constructs and expression system.4. Managing development projects with external partners and outsourcing activities.5. Writing technical reports and presenting data in project and group meetings.6. Supervising direct reports as functional team grows.Qualification requirements1. PhD in Biological Sciences, Molecular Biology, Biochemical Engineering with over 6-8 years of industrial cell line development experience2. Extensive experience with generating high-producing mammalian production cell line.3. Experience with DNA cloning, vector design and construction, and genetic characterization of production cell banks is required.4. Experience with high throughput immunological assays such as Octet assay, ELISA, and FACS analysis.5. Extensive and hands on experience with FACS Sorting.6. In depth knowledge of antibody technology, protein expression, and regulatory guideline for recombinant protein expression. 职能类别： 生物工程/生物制药
联系方式
浦口高新区南京医药谷
公司信息
南京博斯金生物技术有限公司（Biosynergics Inc.）是一家专注于开发治疗和诊断用抗体的创新型生物技术公司。 依托其专有的整合型抗体开发技术平台（H3抗体技术、协同抗体技术［SynAb?］、抗体人源化技术以及细胞工程技术等），博斯金生物致力于开发新一代性能独特、产品多样、拥有自主知识产权的治疗(FIC&BIC)或诊断用抗体产品。 本公司运营管理团队由资深抗体专家和具有国际视野的高级管理人员共同组成。公司创始人、总经理陈明久博士拥有近20年海外抗体开发实战经验，曾任美国战略诊断公司（SDIX）资深运营总监，艾伯维公司（Abbvie）资深研究员，曾带领团队完成100多项诊断用及治疗用抗体开发商业服务项目，客户涵盖几十家国际知名跨国制药公司和诊断试剂公司。自2013年创立以来，公司先后获得 “南京321人才计划”项目重点扶持、清华大学专项投资、以及多项天使投资。公司成立以来，成功开发了系列诊断用抗体产品，建立了多项治疗用抗体合作项目，并与国内外多家知名生物制药公司和诊断试剂公司建立了稳定的业务关系。 公司秉承“创新进取，客户至上”的经营理念，追求多元互补的协同加合效应，以期实现创新与产品产业化高效转化。通过建立国际一流的技术团队和管理团队，博斯金生物致力于开发性能卓越具有国际竞争力的生物技术产品，服务于全球生命科学领域，造福于人类健康福祉。
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