• 5-7年经验
  • 博士
  • 招1人
  • 11-09 发布
  • 五险一金
  • 定期体检
  • 带薪年假
  • 员工培训
  • 节日福利

职位描述

职位描述: Duties and Responsibilities-Establish and manage kinase inhibitors in vitro screening platform; recruit, teach and develop biologists and pharmacologists with drug discovery experience.-Design, develop and execute pre-clinical cellular, enzymatic and biological assays; identify final drug targets, final drug candidates and their optimization and the bioassays and pharmacology associated with above.-Analyze and evaluate experimental data for clinical candidate selection.-Track record and report pre-clinical biological activity research progress, find and resolve possible problems on a timely basis.-Conduct high quality technical reports and summaries, strategic plan for different development stages, as well as regular report to the head of the company.-Understand and stay abreast of intellectual property considerations in terms of research direction and final drug target and candidate selection.-Oversee internal staff and Contract Research Organizations (CROs) to meet timelines.-Proactively identify and justify the resource and budget requirements for the Biology department in order to meet company milestones.-Mentor, guide, and develop staff utilizing transparent methods with an emphasis on both metrics and open dialogue to support a positive departmental and corporate culture.-Maintain professional and collaborative relationships with peers and other company staff.Qualifications-Ph.D. in Molecular Pharmacology, Molecular Biology, Cell Biology, Enzymology, Biochemistry, Pharmacology, or related discipline with 5+ years of experience in academia and industry with small molecule oncology drug discovery.-Previous oversea pharmaceutical/biopharmaceutical industry experience in pre-clinical biological activity, pharmacological research, CRO management is strongly preferred.-Ability to independently develop novel assays and cellular models for small molecule drug screening. Proficiency in standard biochemical, cellular and molecular techniques.-Familiarity with the development of drug candidates from target identification, validation, discovery, pharmacological studies, to IND.-Broad and deep understanding of signaling pathways and biological processes implicated in cancer and the mechanisms of action of targeted therapies and mechanisms of acquired resistance.-In-depth understanding of basic in vitro drug screening, and efficacy and safety profile for anti-cancer targeted agents research.-Extensive knowledge of small molecule drug screening assay technologies with hands-on experience developing and performing cellular and enzyme activity in vitro assays.-Hands on experience with, and a broad understanding of, in vitro and in vivo research methods and models used for targeted therapy research and discovery in oncology.-Proficiency in related data analysis software and analytical skills.-Demonstrated management, leadership and teamwork skills.-Proficient oral and written skills in both English and Mandarin.-Sound scientific judgment, Excellent problem solving skills and quality-driven.-Enthusiasm and passion to for conducting creative scientific research.-Ability to work independently to achieve goals and to handle multi-tasks simultaneously. 职能类别: 医药技术研发管理人员 关键字: Director, Biology

联系方式

科技园中区科苑路15号

公司信息

深圳市塔吉瑞生物医药有限公司成立于2014年,是一家中美合资的高科技医药研发公司。公司成立之初已获得国 内著名天使机构投资,注册资金八千万元人民币。公司位于深圳市南山区科技园中区高科技孵化基地科兴科技园,已建有800多平方米的办公室和实验室. 公司将专注于国际前沿的靶向新药研发,并力争成为世界领先的靶向新药研发基地。公司创始人王义汉博士具有多年国际I类新药研发经验,是多个国际I类新药的核心发明人。公司将以王博士为核心,广纳医药界精英组成强大研发团队,开创塔吉瑞的美好未来。 塔吉瑞将发挥国际化、高科技的优势,注重培养员工严谨的科学精神,为员工提供良好的职业生涯发展规划。公司坚持以人为本的用人理念,营造和谐的用人环境,为员工提供良好的事业平台、科学的考评制度与完善的晋升机制,并建立顺畅的沟通渠道。 塔吉瑞的发展需要人才,现诚邀各路英才加入,与公司一起成长,创造辉煌!

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