职位描述
Job description: Develop bioanalytical methods to characterize physicochemical and functional properties of novel biological products.Develop bioanalytical methods for product pharmacokinetics and immunogenicity analysis in toxicity studies.Perform comparability and stability characterization to support product development.Structure and function relationship study to define key quality attributes of novel products.Manage outside contract labs (CROs) on product development activities. Collaborate and support quality control unit of BeiGene Biologics.Report progress regularly and write study reports to program leader.Support regulatory submissions of products from CTA until NDA/BLA. Requirements: A Ph.D. degree with 0-3 years of experience in protein chemistry, molecular biology, analytical biochemistry or related field is required. Good oral and written communication skills are required. Past experience in monoclonal antibody development, characterization, and quality control is preferred. This position may interface with antibody early discovery, antibody manufacture and CMC development, and regulatory affairs. The successful candidate will have the opportunity to be involved in several aspects of monoclonal biologics development from lead discovery until product registration submission. 职能类别: 生物工程/生物制药
公司信息
About BeiGeneBeiGene is a Chinese life sciences biotechnology company based in Beijing that is focused on discovering and developing innovative oncology drugs that will address unmet medical needs in cancers that are prevalent in China and the Asia-Pacific region.Our compound portfolio will encompass novel drugs that evolve out of our discovery laboratories in China and those selected from in-licensing partners for their potential to have high impact in the treatment of Chinese and Asian cancers.To complement our discovery and development capabilities, BeiGene is creating a robust platform in China to enable the identification of specific subsets of patient populations that will identify patients who are most likely to benefit from the use of specific drugs or treatments. Understanding the link between treatment sensitivity and molecular targets will direct us to develop future drug candidates with greater efficacy and safety.We are building core excellence in:1.novel drug discovery in the areas of both small molecules and biologicals2.translational research with an emphasis on biomarker identification and validation in patients3.bioinformatics based on human tumor genotyping and expression profiling4.clinical developmentOur unique organization synergistically combines the strengths of:1.Chinese and Western scientific knowledge and medical practice2.rigor and robustness from large pharma with biotech entrepreneurialism3.Chinese and western start-up cultureBeiGene is headquartered and operates from Beijing, China and has an office in Philadelphia, USA.Beijing OfficeNo.30 Science Park RoadZhong-Guan-Cun Life Science ParkChangping districtBeijing P.R.China102206BeiGene is looking for dedicated, passionate, self-motivated people to help build a rapidly growing and novel drug research & development organization. and we will make great things happen.To apply, please send your resume to us at hr@beigene.com 关于百济神州百济神州是一家总部设在北京的中国生命科学生物科技公司,致力于探索和开发对中国和亚太地区常见癌症有效的新型抗肿瘤药物。我们的研发策略将包括开发我们自己在中国实验室发现的新药和从合作伙伴引进的对中国和亚太地区常见癌症有潜在疗效的新药。为完善我们的研发能力,百济神州正在中国创造一个从实验室到临床试验的强大整合研发平台,用于识别癌症患者中最有可能受益于相关药物或治疗方法的病人亚群。通过理解对药物的敏感性和靶标分子之间的关系, 我们将会研发出更有效和更安全的新药。我们正在以下领域建立杰出的团队:1.全新的小分子药物和生物药物的研发2.侧重于在患者中对生物标志物识别和确认的转化研究3.基于人类肿瘤基因分型和基因表达谱的生物信息学4.临床开发以下几个方面实力的结合带给我们独特的优势:1.中国和西方的研发知识和临床实践2.大制药公司的严谨性和稳健性与小生物技术公司的创业精神3.中国和西方的创业文化百济神州总部设立于中国北京,并于美国费城设有办事处。北京研发中心北京市昌平区中关村生命科学园,科学园路30号邮编:102206应聘者请发简历至hr@beigene.com